Basic Information
VIS ID
TVIS10015755
Fusion event
HBV-chr11 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Host Sequence
Chromosome
chr11
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
87566555/87855663 (Hg38)
End
87566555/87855663 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11F
Target gene
LOC107984361 ; RAB38
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-let-7b-5p ; hsa-mir-30a-5p
Nearest miRNA
hsa-mir-10392/Upstream/1577265; hsa-let-7a-2/Downstream/320839;
Nearest TSS
ENST00000527297/Upstream/136252; ENST00000532849/Downstream/194443;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/817612, chr11-CpG: 45/Downstream/319412
Upstream sequence
TTTAAGGATGATAAGATAAAAGAAATTACGT
Junction sequence
TTTAAGGATGATAAGATAAAAGAAATTACGTAATATGGCGACCCACAAAATGAGGCGCTGAGTGTAGTTTCTCTCTTATATAACATGC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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