VISDB Viral Integration Site DataBase

VIS ID

TVIS10015757

Fusion event

HBV-SMAD5 integration

Validated

No

Detection method

MAPS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

AY800389.1;AY800390.1;AY800391.1;AY800392.1

Orient

+

Chromosome

chr5

Cytoband

q31.1

Reference genome

Start

End

135491847/136156158 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-130a-3p ; hsa-mir-186-5p ; hsa-mir-16-5p ; hsa-mir-135a-5p ; hsa-mir-145-5p ; hsa-mir-135b-5p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-3133 ; hsa-mir-377-5p ; hsa-mir-329-5p ; hsa-mir-655-5p ; hsa-mir-1304-5p ; hsa-mir-2052 ; hsa-mir-6086 ; hsa-mir-7856-5p ; hsa-mir-4742-3p ; hsa-mir-299-3p ; hsa-mir-3658 ; hsa-mir-8055 ; hsa-mir-3653-3p ; hsa-mir-4477a ; hsa-mir-675-3p ; hsa-mir-4766-3p ; hsa-mir-657 ; hsa-mir-548p ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-4322 ; hsa-mir-4296 ; hsa-mir-4265 ; hsa-mir-4417 ; hsa-mir-6721-5p ; hsa-mir-4736 ; hsa-mir-3692-3p ; hsa-mir-4511 ; hsa-mir-4279 ; hsa-mir-6881-3p ; hsa-mir-302a-5p ; hsa-mir-877-3p ; hsa-mir-222-3p ; hsa-mir-548a-3p ; hsa-mir-23a-3p ; hsa-mir-27a-3p ; hsa-mir-34a-3p ; hsa-mir-3659 ; hsa-mir-4252 ; hsa-mir-4668-3p ; hsa-mir-5690 ; hsa-mir-6889-3p

Nearest miRNA

hsa-mir-10397/Upstream/353083; hsa-mir-103a-1/Downstream/1491414;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/22685, chr5-CpG: 171/Downstream/35210

Upstream sequence

GAATGTGAACTACCTATAAAGA

Junction sequence