Basic Information
VIS ID
TVIS10015764
Fusion event
HBV-chr18 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Host Sequence
Chromosome
chr18
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
57749625/60082393 (Hg38)
End
57749625/60082393 (Hg38)
Orient
-
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/1631235; hsa-mir-5011/Downstream/6999191;
Nearest TSS
ENST00000575820/Upstream/72112; ENST00000588794/Downstream/42640;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/112498, chr18-CpG: 98/Downstream/1251057
Upstream sequence
TCTGTGTGGCTATTAGCAAGTGATATAGTTTT
Junction sequence
TCTGTGTGGCTATTAGCAAGTGATATAGTTTTCATGGTGCTGGTGAACAGACCAATTTATGCCTACAGCCTCCTAGTACAAAGATCAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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