MEIS3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015810
Fusion event
HBV-MEIS3 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
47908418/47405161 (Hg38)
End
47908418/47405161 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
MEIS3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-130b-5p
Nearest miRNA
hsa-mir-10395/Upstream/178140; hsa-let-7e/Downstream/1604745;
Nearest TSS
ENST00000633603/Upstream/32364; ENST00000593284/Downstream/3991;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/55440, chr19-CpG: 43/Downstream/1689
Upstream sequence
ACTATTAACAATTTTAATTTCATAGATAAGAAGACTG
Junction sequence
ACTATTAACAATTTTAATTTCATAGATAAGAAGACTGGTGAACACACCAATTTATGCCTACAGCCTCCTAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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