PLCB1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015814
Fusion event
HBV-PLCB1 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
-
Host Sequence
Chromosome
chr20
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
8629711/8649064 (Hg38)
End
8629711/8649064 (Hg38)
Orient
-
Location type
Intronic
Target gene
PLCB1
miRNAs that regulate target gene
hsa-mir-423-5p ; hsa-mir-30c-5p ; hsa-mir-297 ; hsa-mir-4325 ; hsa-mir-6867-5p ; hsa-mir-567 ; hsa-mir-223-5p ; hsa-mir-3607-5p ; hsa-mir-511-3p ; hsa-mir-502-3p ; hsa-mir-501-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/1277372; hsa-mir-1-1/Downstream/2000572;
Nearest TSS
ENST00000382410/Upstream/20776; ENST00000475958/Downstream/327;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/516119, chr20-CpG: 107/Downstream/419247
Upstream sequence
AGACACCTTGGGGCAATGGGTAGTAGCAGCAAGG
Junction sequence
AGACACCTTGGGGCAATGGGTAGTAGCAGCAAGGGTGCTGGTGAACACACCAATTTATGCCTACAGCCTCC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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