VISDB - VIS Detail

Expression analysis of TCGA samples

Basic Information

VIS ID

TVIS10015819

Fusion event

HBV-SESTD1 integration

Validated

No

Detection method

MAPS

Data source

Curated

Sample type

Adjacent tissue

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2012

PubMed ID

23236287

Virus Sequence

Virus name

HBV

Reference genome

AY800389.1;AY800390.1;AY800391.1;AY800392.1

Orient

+

Host Sequence

Chromosome

chr2

Cytoband

q31.2

Reference genome

GRCh37/hg19

Start

180040114/179175387 (Hg38)

End

180040114/179175387 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA2G

Target gene

SESTD1

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-130b-3p ; hsa-mir-148a-3p ; hsa-mir-21-5p ; hsa-mir-19b-3p ; hsa-mir-4523 ; hsa-mir-4422 ; hsa-mir-1276 ; hsa-mir-548e-5p ; hsa-mir-3151-5p ; hsa-mir-92a-2-5p ; hsa-mir-3165 ; hsa-mir-6880-5p ; hsa-mir-8071 ; hsa-mir-4483 ; hsa-mir-1293 ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-6782-5p ; hsa-mir-6732-5p ; hsa-mir-3936 ; hsa-mir-548s ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-3926 ; hsa-mir-103b ; hsa-mir-646 ; hsa-mir-5197-5p ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-195-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-497-5p ; hsa-mir-16-5p ; hsa-mir-424-5p ; hsa-mir-552-5p ; hsa-mir-4652-3p ; hsa-mir-4528 ; hsa-mir-3150b-5p ; hsa-mir-3150a-5p ; hsa-mir-4668-5p ; hsa-mir-371a-5p ; hsa-mir-4668-3p ; hsa-mir-548c-3p

Nearest miRNA

hsa-mir-10b/Upstream/1861505; hsa-mir-1244-1/Downstream/685449;

Nearest TSS

ENST00000437798/Upstream/26006; ENST00000419129/Downstream/16479;

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/694357, chr2-CpG: 112/Downstream/88504

Upstream sequence

TCAACAAATAAGGTAGCTACTTTAGGGTTCTGTGGA

Junction sequence

TCAACAAATAAGGTAGCTACTTTAGGGTTCTGTGGAAAGACCTTTAACCTAATCTCCTCCCCCAACTCCTC

* Color: Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence

Reference

Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.