HPSE2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015837
Fusion event
HBV-HPSE2 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr10
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
100854817/99095060 (Hg38)
End
100854817/99095060 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
HPSE2
Nearest miRNA
hsa-mir-107/Upstream/170492; hsa-mir-1307/Downstream/1879925;
Nearest TSS
ENST00000439456/Upstream/350989; ENST00000488090/Downstream/140742;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/626985, chr10-CpG: 46/Downstream/137315
Upstream sequence
CTCAGCCTCCCTAAGATGGGACTACAGGC
Junction sequence
CTCAGCCTCCCTAAGATGGGACTACAGGCAAAGACCTTTAACCTAATCTCCTCCCCCAACTCCTCCCAGTC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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