Basic Information
VIS ID
TVIS10015848
Fusion event
HBV-chr12 integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr12
Cytoband
q24.23
Reference genome
GRCh37/hg19
Start
120121955/119684150 (Hg38)
End
120121955/119684150 (Hg38)
Orient
+
Fragile sites / regions
FRA12E ; FRA12C
Nearest miRNA
hsa-let-7i/Upstream/3255832; hsa-mir-1178/Downstream/29484;
Nearest TSS
ENST00000382841/Upstream/4072; ENST00000535109/Downstream/13959;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/15723, chr12-CpG: 31/Downstream/6018
Nearby gene
CIT(+) ;
Upstream sequence
TAATGATGTCTAAAGCATGTAGACCGTGGCTCTA
Junction sequence
TAATGATGTCTAAAGCATGTAGACCGTGGCTCTAGTTTATGCCTACAGCCTCCTAGTACAAAGACCTTTAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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