LRP1B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015853
Fusion event
HBV-LRP1B integration
Validated
No
Detection method
MAPS
Data source
Curated
Sample type
Adjacent tissue
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2012
PubMed ID
23236287
Virus Sequence
Virus name
HBV
Reference genome
AY800389.1;AY800390.1;AY800391.1;AY800392.1
Orient
+
Host Sequence
Chromosome
chr2
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
141083418/140325849 (Hg38)
End
141083418/140325849 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LRP1B
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-200c-3p ; hsa-mir-106b-3p ; hsa-mir-5692a
Nearest miRNA
hsa-mir-128-1/Upstream/4660371; hsa-mir-10b/Downstream/260777;
Nearest TSS
ENST00000437798/Upstream/27880; ENST00000410015/Downstream/32219;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1544769, chr2-CpG: 58/Downstream/1804306
Nearest cancer related gene
LRP1B(TSG, No orient, 0)
Upstream sequence
AGGTTTGGCTGTGGATTATTTTAGTGAACGC
Junction sequence
AGGTTTGGCTGTGGATTATTTTAGTGAACGCAAAGTTGCATGGTGCTGGTGAACAGACCAATTTATGCCTA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Ding, D., et al. Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet ,2010,8(12): e1003065.
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