Basic Information
VIS ID
TVIS10015862
Fusion event
HBV-chr11:q14.1 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1705
Orient
+
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
83163665/83452622 (Hg38)
End
83163665/83452622 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10392/Upstream/1561786; hsa-let-7a-2/Downstream/2825711;
Nearest TSS
ENST00000527297/Upstream/166215; ENST00000531424/Downstream/9527;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/166129, chr11-CpG: 24/Downstream/2175677
Nearby gene
DLG2
Upstream sequence
GCTCAATAGTTCCTTGTTTTTATTTTAGGATTCTTGCTTGGATAGCTATTGAATACTAGTGGCATGGAACAGGCAGGAGATAAATGGCCTGATACACGGT
Downstream sequence
ACAGGTTCTGGCTGAAGTATGTTTTTTTTAAATTCATGCTGAATGACTTGCTTGCACAGCAATACTCCAAATTGTTTTTTCATACATAGTTCACCTAACT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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