Basic Information
VIS ID
TVIS10015868
Fusion event
HBV-chr11:q13.1 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1840
Orient
-
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64200314/64432842 (Hg38)
End
64200314/64432842 (Hg38)
Orient
+
Fragile sites / regions
FRA11H
Nearest miRNA
hsa-mir-1237/Upstream/64139; hsa-let-7a-2/Downstream/445681;
Nearest TSS
ENST00000527297/Upstream/12307; ENST00000316124/Downstream/16232;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/62127, chr11-CpG: 21/Downstream/16097
Nearby gene
MIR1237
Upstream sequence
AATTTCAAGCCTAGAggccaggcacagtggctcacgcctgtaatcccagcactttgggaagtcaagggaggtcaggactttgagaccagcctgatccacg
Downstream sequence
tggagaaaccccgtgtctactaaaaatacaaaattaaccaagcatggtggcacatgcctgtaatccctgctaggcaggaaggctgaggcaggagaatcgc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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