Basic Information
VIS ID
TVIS10015875
Fusion event
HBV-chr4:q35.2 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1462
Orient
+
Host Sequence
Chromosome
chr4
Cytoband
q35.2
Reference genome
GRCh37/hg19
Start
190666407/189745253 (Hg38)
End
190666407/189745253 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12113/Upstream/4806813;
Nearest TSS
ENST00000502981/Upstream/40763; ENST00000503609/Downstream/136262;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/98685, chr4-CpG: 66/Downstream/65239
Upstream sequence
GAGTCGGCCTTGAGGAAGCAGTCCTTATACCTCAAGTTCGACCCCCTCCTGAGGGACAGTCCTGGTAGACCAGTGCCCGTGGCCACCGAGACCAGCAGGT
Downstream sequence
aggccactaaatgtgtctcggccgggtgtggtggctcacacctgtaatcccagcactttgggaggccaaggcagacatatcacctgaggtcaagagtttg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate