Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015876
Fusion event
HBV-TCF7L2 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1390
Orient
+
Host Sequence
Chromosome
chr10
Cytoband
q25.2
Reference genome
End
114925588/113165829 (Hg38)
Orient
-
Location type
Exon
Target gene
miRNAs that regulate target gene
hsa-mir-324-5p ; hsa-mir-148b-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-3613-3p ; hsa-mir-4435 ; hsa-mir-1298-5p ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-539-5p ; hsa-mir-3190-5p ; hsa-mir-4793-3p ; hsa-mir-3919 ; hsa-mir-892b ; hsa-mir-6807-3p ; hsa-mir-217 ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-1-5p ; hsa-mir-193a-3p ; hsa-mir-193b-3p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-651-5p ; hsa-mir-3117-3p ; hsa-mir-891b ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-5193 ; hsa-mir-8083 ; hsa-mir-4759 ; hsa-mir-3169 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-3666 ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-155-3p ; hsa-mir-32-3p ; hsa-mir-1305 ; hsa-mir-421 ; hsa-mir-7159-5p ; hsa-mir-8485 ; hsa-mir-505-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-623 ; hsa-mir-6832-3p ; hsa-mir-3938 ; hsa-mir-4717-5p ; hsa-mir-4753-5p ; hsa-mir-6768-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-26a-1-3p
Nearest miRNA
hsa-mir-107/Upstream/531575; hsa-mir-202/Downstream/612164;
Nearest CpG islands
chr10-CpG: 16/Target, None/Upstream, None/Downstream
Nearest cancer related gene
TCF7L2(TSG, No orient, 0)
Upstream sequence
aatggaatggaatggaatagtcaatgaactcgaatggaatcatcattgaatggaatcgaatggaatcatcgagtggaatcaaatggaatcatgatcaaat
Downstream sequence
ggaatcgaatgtaatcatcatcaaatggaatcaaaaataaccataatcaattggtattgaatggaattgtcatcaaatggaattcaatggaatcatcatc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.