Basic Information
VIS ID
TVIS10015878
Fusion event
HBV-chr2:p11.2 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1868
Orient
-
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
86622425/86395302 (Hg38)
End
86622425/86395302 (Hg38)
Orient
-
Fragile sites / regions
FRA2S ; FRA2L
Nearest miRNA
hsa-mir-1285-2/Upstream/202194; hsa-mir-10b/Downstream/799484;
Nearest TSS
ENST00000437798/Upstream/57219; ENST00000498528/Downstream/45345;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/57357, chr2-CpG: 136/Downstream/45390
Nearby gene
KDM3A
Nearest cancer related gene
KDM3A(TSG, No orient)
Upstream sequence
TTCCACCCGGAATCCCGACACGGTGTCGGAAGCTGAGACCCAGGAGACCACAAAGCTACTGGCTGTGATTTCGGTCACAGATTCAGAAGTGGCCACAAGA
Downstream sequence
CTCAAATCTACAGCTTGGAGTAGGTTGATTTCCCTGCCTGTTTCCCAGGGAAGCGTTGCACTACCCATATGGCAGCTTTCTCATACTCCCTGTCTGCATT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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