Basic Information
VIS ID
TVIS10015879
Fusion event
HBV-chr7:p22.1 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1808
Orient
+
Host Sequence
Chromosome
chr7
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
6955583/6915952 (Hg38)
End
6955583/6915952 (Hg38)
Orient
+
Fragile sites / regions
FRA7B
Nearest miRNA
hsa-mir-339/Upstream/1204042; hsa-mir-10399/Downstream/151012;
Nearest TSS
ENST00000635602/Upstream/89182; ENST00000467716/Downstream/240982;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/60038, chr7-CpG: 16/Downstream/19174
Nearby gene
CCZ1B
Upstream sequence
aaataaactagtcaaatgttcagcatgtgagttggtgatgaCAgcacggtgcttcatgcctgtaatcctagtgctttgggaggccgagatgtgaggatgg
Downstream sequence
CACTCAGGGTTGCTAACCAGTCAGAAGGACCAACAGAGCTCGACAAACAGACAAGAGGGAGAAGGGCACCACCTTCCAACCTACCCGCTTAGACAGCCTT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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