Basic Information
VIS ID
TVIS10015881
Fusion event
HBV-LOC101927573 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1819
Orient
+
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
109468840/107709082 (Hg38)
End
109468840/107709082 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
LOC101927573
Nearest miRNA
hsa-mir-107/Upstream/3440677; hsa-mir-202/Downstream/3189008;
Nearest TSS
ENST00000439456/Upstream/544548; ENST00000421481/Downstream/331617;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/544035, chr10-CpG: 80/Downstream/205356
Upstream sequence
tgcaaatgttactgggattcctataaaactacttttctcttttaaacctgcccttatgagtctttaaagaaattcttacattctggcacaatttgatgtt
Downstream sequence
caaagctcagaatcttaacctatcccaagtctagaattggccatGTGCACTTCTAGTGGTCAAAGGTTGTTAGAAACTGGCTCTGGTTCATAGAGTTGCT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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