Basic Information
VIS ID
TVIS10015882
Fusion event
HBV-chr1:p31.3 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1756
Orient
+
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
63211678/62746007 (Hg38)
End
63211678/62746007 (Hg38)
Orient
+
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-12132/Upstream/667148; hsa-mir-101-1/Downstream/580918;
Nearest TSS
ENST00000473358/Upstream/57525; ENST00000443289/Downstream/38128;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/57329, chr1-CpG: 599/Downstream/570716
Nearby gene
ATG4C
Upstream sequence
TGTTACAGGAAATCTATTTCTAGCTGTCCAATTAATTAAATAGATTTAAAGACTAATACTTGATATGCCAAGGGCAGAACAAAAGCCTAGCCTAGAGGGA
Downstream sequence
TTGGATCCTCTTCTTTTTCTAGCCCCCTTTATTTCTAGGAGTCCATTACACCTAGATTTTGTTTGCATTTGTCTCAGTTTGCTTCATTCTGTACATTTCC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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