Basic Information
VIS ID
TVIS10015886
Fusion event
HBV-chr10:q26.11 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1717
Orient
+
Host Sequence
Chromosome
chr10
Cytoband
q26.11
Reference genome
GRCh37/hg19
Start
120628434/118868922 (Hg38)
End
120628434/118868922 (Hg38)
Orient
+
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/1701148; hsa-mir-202/Downstream/509050;
Nearest TSS
ENST00000439456/Upstream/113673; ENST00000340087/Downstream/134962;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/113326, chr10-CpG: 176/Downstream/160355
Nearby gene
RPL17P36(+3092) ;
Upstream sequence
GGAATGAAAGTAGAGTTTGTTAAGATGACCCCAAAACAAGCATGTAAAACAGAACAAGGTAGGTGCATCAAGCCATGCCATTTGCGAGATACTCAGAAAA
Downstream sequence
CAAAGGCATTGTTTGTGCCTTTTTACAAGCCATGGGTTAAGAGGTGTCACTAAGtgccaaaaattcaccctgtgcccctaggccagtcacttctctatgg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate