Basic Information
VIS ID
TVIS10015891
Fusion event
HBV-chr15:q22.2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1820
Orient
-
Host Sequence
Chromosome
chr15
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
60237451/59945252 (Hg38)
End
60237451/59945252 (Hg38)
Orient
-
Fragile sites / regions
FRA15A
Nearest miRNA
hsa-mir-10393/Upstream/773990; hsa-mir-11181/Downstream/2359406;
Nearest TSS
ENST00000557528/Upstream/255718; ENST00000396057/Downstream/58970;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/255656, chr15-CpG: 17/Downstream/49991
Nearby gene
FOXB1
Upstream sequence
cttcacagactaatacaACCCGAGAGAAATTCTTTAGGAGTCTGACTCCTATAGAACTAGTTAAACAACAGTGGATACATtttagaattaagctgaaaaa
Downstream sequence
CAGTAGTTGCAGTATCAAGAAGCTACTGACATGGATCTGAAATGACTTTTATAACAGCGGCAACAAAAAAAGGCCTCAGCTGCCTCTAGGAACGCATCTA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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