ATP11B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015894
Fusion event
HBV-ATP11B integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1827
Orient
+
Host Sequence
Chromosome
chr3
Cytoband
q26.33
Reference genome
GRCh37/hg19
Start
182599673/182881885 (Hg38)
End
182599673/182881885 (Hg38)
Orient
-
Location type
Intron
Fragile sites / regions
FRA3C
Target gene
ATP11B
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-652-3p ; hsa-mir-222-3p
Nearest miRNA
hsa-let-7g/Upstream/6366734; hsa-mir-1224/Downstream/1004915;
Nearest TSS
ENST00000440867/Upstream/2346; ENST00000475636/Downstream/15417;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/87391, chr3-CpG: 91/Downstream/98076
Upstream sequence
aggtgcccagtaccgcgagtgcctgctctgttctaagctttcctggtgcctagcttaggtctcagccttctcttggtctgccagtgaggtgttatttggc
Downstream sequence
CGATAAACACAACATCTCAAGTAGTTTTCTCATTTTAATAACCTTTATCCTTATTCTTTTCTATTTTTGCCTAAAACTTTTATTAGATTCAGACTGCTAA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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