UBAP2L _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015895
Fusion event
HBV-UBAP2L integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1819
Orient
+
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
154239263/154266787 (Hg38)
End
154239263/154266787 (Hg38)
Orient
+
Location type
Intron
Fragile sites / regions
FRA1F
Target gene
UBAP2L
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-760 ; hsa-mir-93-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-125b-5p ; hsa-mir-93-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7a-5p ; hsa-mir-3679-3p ; hsa-mir-2355-5p ; hsa-mir-6793-3p ; hsa-mir-5092
Nearest miRNA
hsa-mir-101-1/Upstream/73044; hsa-mir-1182/Downstream/708906;
Nearest TSS
ENST00000473358/Upstream/335; ENST00000477780/Downstream/5724;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/45475, chr1-CpG: 43/Downstream/5447
Upstream sequence
ccttactacctctcactcatccctcaagttctctcttacccatgtcttatcccccaacctcaatcccatccctctctgataactcctccctgtacccatt
Downstream sequence
gctttcccttcaatacacttgtcaatttttaacttgtacgatattgtctgtctccccactaaactgaaagcacaacgagggcagaaactgtgtctatttg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate