DCHS2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015899
Fusion event
HBV-DCHS2 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1838
Orient
-
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
155171488/154250336 (Hg38)
End
155171488/154250336 (Hg38)
Orient
-
Location type
Intron
Target gene
DCHS2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-12113/Upstream/1713820; hsa-mir-1305/Downstream/4878466;
Nearest TSS
ENST00000502981/Upstream/14356; ENST00000623885/Downstream/11399;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/457248, chr4-CpG: 39/Downstream/82642
Upstream sequence
ACAATGTTCTAACACAGATAACATATGAGTGAGCTCGAAACAATTATAGTAAAACACCAGCCAGGGGTAGCCAAGGTGACGTTTGATAATGACACACAGT
Downstream sequence
tggtgataagtcaccactcctcaattctcattttacatattctccctaggtaattcattttacacattttccctggatgaatctcaaatccatatcttga
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate