Fusion event
HBV-LCN12 integration
Detection method
Alu PCR and sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reference genome
Not given
End
139845988/136951536 (Hg38)
Nearest miRNA
hsa-let-7a-1/Upstream/64733; hsa-mir-3621/Downstream/217650;
Upstream sequence
GAGAGGAAGAGGAGCCCCAGGTTTGAAGTGACTTTAAGGAGTATCTGTCTGCTGCAATCTCTGCAATCTCTGCCTGCAGTCTTGCATAGATGGGGAACTC
Downstream sequence
TATCATTCAATGTGATTTATTTAGAAGTTTCTTAGTTTTCTCTAGCTTTTTTTGTCCGCTATGCAGCAATGCTAACTCAACATAAACAAAGGACATCTCG
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.