Fusion event
HBV-chr9:q34.2 integration
Detection method
Alu PCR and sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reference genome
Not given
End
136346366/133481244 (Hg38)
Nearest miRNA
hsa-let-7a-1/Upstream/429185; hsa-mir-126/Downstream/898167;
Upstream sequence
ATGACTAAAACTGTTCTTTTCACTTTCAAAAGAATTCACCATTCATCCCCTAGTCTAATTAGCCCATGAGAGGCTTGTCACTTAAAGGAGCTTGTTCCAT
Downstream sequence
GGCTCCCGCCAGCAAACGTGATGATTTACTTTCTGTGTTCTGTTCTGCTTCCTGTCTTGTCCCCCACCTACTCCCACCCAGACccgtcacctgagtgtca
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.