Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015911
Fusion event
HBV-ANKRD11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1837
Orient
-
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
Start
End
89385728/89319320 (Hg38)
Orient
+
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-1914-3p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-186-5p ; hsa-mir-149-5p ; hsa-mir-4699-3p ; hsa-mir-4766-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-4684-3p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-605-3p ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-3154 ; hsa-mir-8066 ; hsa-mir-3714 ; hsa-mir-6809-5p ; hsa-mir-4330 ; hsa-mir-4698 ; hsa-mir-651-3p ; hsa-mir-4311 ; hsa-mir-365b-3p ; hsa-mir-365a-3p
Nearest miRNA
hsa-mir-11401/Upstream/602983;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/12214, chr16-CpG: 19/Downstream/22509
Upstream sequence
aattcaaaatcagctgacttgggacctgaattagagctgcaaaaatctgttcactgttgctacaACCTACAGGCAAGTCTAACATTTTAACCGCCCTTTC
Downstream sequence
CCCAGGCACCTTCCCCAATGGACCAGGGATCTGGGAGTCCACTCAGGAGGTGGAGGAAGTGGGTCGCACCCACCAGGCAAAATACTTTTCACGGCCTGCA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.