Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015914
Fusion event
HBV-C3orf33 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1703
Orient
+
Host Sequence
Chromosome
chr3
Cytoband
q25.31
Reference genome
End
155498844/155781055 (Hg38)
Orient
-
Location type
Intron
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-4799-5p ; hsa-mir-4789-3p ; hsa-mir-627-3p ; hsa-mir-4803 ; hsa-mir-1273e ; hsa-mir-1827 ; hsa-mir-3664-3p ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4478 ; hsa-mir-4649-3p ; hsa-mir-4695-5p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-485-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-665 ; hsa-mir-6808-5p ; hsa-mir-6884-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-940
Nearest miRNA
hsa-let-7g/Upstream/4215060; hsa-mir-1224/Downstream/3501591;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/36283, chr3-CpG: 53/Downstream/24896
Upstream sequence
GAAGTAAGTGTTAATTTGAAAAACAGGAGATGTGTGGTTATATTTGAGAGAACTTTTCTAAACTTTTAATACGAAGGAAAATCTGAAAGTTATAATCCTA
Downstream sequence
ggcgcaatctcggctcactgcaagctccgcttcccgggttcacgccattctcctgcctcagcctcccgagtagctgggactacaggcgtccgccaccgcg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.