DDX54 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015917
Fusion event
HBV-DDX54 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1832
Orient
-
Host Sequence
Chromosome
chr12
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
113606823/113169018 (Hg38)
End
113606823/113169018 (Hg38)
Orient
+
Location type
Intron
Fragile sites / regions
FRA12E ; FRA12D
Target gene
DDX54
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-16-5p ; hsa-mir-744-5p ; hsa-mir-423-5p ; hsa-mir-484 ; hsa-mir-10a-5p
Nearest miRNA
hsa-let-7i/Upstream/9841; hsa-mir-1178/Downstream/122505;
Nearest TSS
ENST00000382841/Upstream/3146; ENST00000615042/Downstream/8345;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/14203, chr12-CpG: 115/Downstream/15938
Upstream sequence
AGGCGTGGACCCCGCCGCAGCTCCTCTGACATTGCCCGTGCCAAGATTCAGGGCAAGTGCCACCGGGTGAGCTGCTTGTTGTAGAGCCAGATGCCTTTAA
Downstream sequence
ACTGGGTCTTTTTTTCTTTCCCTGCAGGGCAATTCATTTGCCCAGGTAAGAGGGTGTGAGATGAGAACTCTGGTTTCACATTGATTGCATTACTACAAAT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate