FN1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015920
Fusion event
HBV-FN1 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1940
Orient
+
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
216251299/215386576 (Hg38)
End
216251299/215386576 (Hg38)
Orient
-
Location type
Exon
Target gene
FN1
miRNAs that regulate target gene
hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p
Nearest miRNA
hsa-mir-10b/Upstream/1628417; hsa-mir-1244-1/Downstream/2513937;
Nearest TSS
ENST00000437798/Upstream/2496; ENST00000412951/Downstream/6571;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/74167, chr2-CpG: 43/Downstream/48968
Upstream sequence
GGGTCTCCATGAAACAGAGCAAATATGTGACTTATTTGCAAGTTCAACACTTAAATACAATCTCATGGCTCACCAGCCTCTGAGAACCATTGCACTTGAA
Downstream sequence
ttttttttttttttttttGAGAGCTGATGACAGACAACAGCAAGCTACTTTACAGAATCTACCAACTGGGTAGGAAAGTCTTCTGAGTTTCTTTGCAGAC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate