Basic Information
VIS ID
TVIS10015921
Fusion event
HBV-LOC105375716 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1783
Orient
+
Host Sequence
Chromosome
chr8
Cytoband
q24.11
Reference genome
GRCh37/hg19
Start
118467464/117455225 (Hg38)
End
118467464/117455225 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105375716
Nearest miRNA
hsa-mir-12123/Upstream/580425; hsa-mir-10400/Downstream/1869946;
Nearest TSS
ENST00000518652/Upstream/319897; ENST00000519879/Downstream/65488;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/516505, chr8-CpG: 45/Downstream/65391
Nearby gene
MED30
Upstream sequence
ACTAGTATGGTATCATGAACCTATGGGTAAGGTAGACCACTAATGTGCAATTCTATCAGGTCTAAGTGGCCAATAAATATTATTAATCTCCCATCATAAA
Downstream sequence
cccttcatgctaaaaactcaataaattaggtattgatgggatgtatctcaaaataataagagctatttatgacaaacccacagccaatatcatactgaat
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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