Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015923
Fusion event
HBV-TC2N integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1694
Orient
+
Host Sequence
Chromosome
chr14
Cytoband
q32.2
Reference genome
Start
End
92258480/91792136 (Hg38)
Orient
-
Location type
Intron
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1260a/Upstream/14525846; hsa-mir-1185-1/Downstream/2156090;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/217604, chr14-CpG: 57/Downstream/43721
Upstream sequence
ACACTCGTTCACATCTGTGGAAAGCCAAGGCACATTGCTGACTGTCCTCCCAACAGAACAGCCACAATAACTAGGCAGAAAAAGCACCAGCAACGAAATC
Downstream sequence
gaaaTGTGCTAGGAGAAGGTAACCCTGAGGTTATTTTCCAATGGAGAAAGAAAACAGTTCTGTTAACATTTTATCAATAATTTCTAAATATTTGAAAATA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.