Basic Information
VIS ID
TVIS10015925
Fusion event
HBV-chr21:q21.1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1823
Orient
-
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
20990375/19618061 (Hg38)
End
20990375/19618061 (Hg38)
Orient
-
Nearest miRNA
hsa-let-7c/Upstream/931897; hsa-mir-155/Downstream/3461223;
Nearest TSS
ENST00000624081/Upstream/316448; ENST00000486367/Downstream/281694;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/1372504, chr21-CpG: 89/Downstream/1379044
Nearby gene
NIPA2P3(+2691) ;
Upstream sequence
TATGTGTAATATTAGGTCGTTTGTAATTAAGGAATATTTAAAGTAAATTTAAACATTAAATGCAGGTAACAATCTAACATATACATCATAAATATGAAAA
Downstream sequence
TGATTCTTTAGGCCTGTTTAACATTATAATGTAAAGATTACAGAAAAATGAATATACTAGGAGGGATATAAGTAGGTACCCATAAAGATTATATTCCAGG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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