Basic Information
VIS ID
TVIS10015929
Fusion event
HBV-chr5:q21.1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1845
Orient
-
Host Sequence
Chromosome
chr5
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
99384998/100049294 (Hg38)
End
99384998/100049294 (Hg38)
Orient
+
Fragile sites / regions
FRA5F
Nearest miRNA
hsa-mir-10397/Upstream/3970082; hsa-mir-103a-1/Downstream/767188;
Nearest TSS
ENST00000502646/Upstream/499862; ENST00000511468/Downstream/352147;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1119467, chr5-CpG: 62/Downstream/485927
Nearby gene
MTCYBP22(-509) ; MTATP6P2(+1425) ;
Upstream sequence
AAAGGAGGTAAAAGTTTTGAGATTTTTCATGAATGAAAATGtttcacatgcttgttggccatgtatatgttgtcttttgaaaagtatctgttcatgtcct
Downstream sequence
GGCTATTAGTGGGAGTAGGGTTTGAAGTCCTTGAGAGAGAATTATGATGCGGCTGTGGGTTCGCTCGTAGTTTGAGTTTGCTAGGCAGAAAAATAAGGAG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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