Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015931
Fusion event
HBV-RASAL2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1807
Orient
+
Host Sequence
Chromosome
chr1
Cytoband
q25.2
Reference genome
End
178370986/178401851 (Hg38)
Orient
+
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-15a-3p ; hsa-mir-125b-5p ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-203a-3p ; hsa-mir-6867-5p ; hsa-mir-511-3p ; hsa-mir-5583-3p ; hsa-mir-129-5p ; hsa-mir-4639-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-136-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1372406; hsa-mir-1182/Downstream/275898;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/307140, chr1-CpG: 49/Downstream/84813
Nearest cancer related gene
RASAL2(TSG, No orient, 0)
Upstream sequence
GGTTTATCTGCATCCCAGAAACTCACAGTTCACTGTGCTTTGCTAGACAAGTAGAATATTTAGAAGTTTTGACCATCTAAAAGGACATTTTAGATGAAGG
Downstream sequence
ACTATCCCCCTTTGAAGTTCACAAATATTTGAATGTCCTTTCAATTGCTTAGATACCTTACTCTTCTCAAAATCAGGGCAGAGGTGACTGCTGGGAGCCA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.