Basic Information
VIS ID
TVIS10015932
Fusion event
HBV-chr6:p12.3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1470
Orient
-
Host Sequence
Chromosome
chr6
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
50309423/50341710 (Hg38)
End
50309423/50341710 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10398/Upstream/5143940; hsa-mir-10524/Downstream/1802639;
Nearest TSS
ENST00000381078/Upstream/247999; ENST00000426547/Downstream/172325;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/790237, chr6-CpG: 57/Downstream/372911
Upstream sequence
AACAAAAGCAAATAAGTGGAGTCAAACCTATATGTTTGTAAAAGTGTGCTATGTGGGTATGTGTATGCATGAGTCTATGTGTATATAGGGAGGGAGTGGA
Downstream sequence
TGCTTCTAGAGAAAATCCTCCACAAAAAAGAGAACTTGAAATGCTGAGTAAAAATACCATATAAAACATTTGCTGCAGCATTTGAAACCATCTTATCAAT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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