Basic Information
VIS ID
TVIS10015937
Fusion event
HBV-chr14:q32.11 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1821
Orient
-
Host Sequence
Chromosome
chr14
Cytoband
q32.11
Reference genome
GRCh37/hg19
Start
91309115/90842771 (Hg38)
End
91309115/90842771 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1260a/Upstream/13576481; hsa-mir-1185-1/Downstream/3105455;
Nearest TSS
ENST00000550708/Upstream/14643; ENST00000521081/Downstream/68698;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/26167, chr14-CpG: 134/Downstream/217118
Nearby gene
RPS6KA5
Upstream sequence
ATGCAAAAGAGAAATGTTCAAAAGTCAGTATTTGTTTTAAAAATTTAGTTAAATATCACTATAACCTGGCAAGCCATAAACATCTTCTTTAGACAACTAA
Downstream sequence
TTGAGCTGAGGATTTTTTCAGTCTACTGCACCTCCTTCTCGTCCTAATAATAACCACACTGTAGAGGTGGGGGGAGCTCTTGAGGCCCAAATTGTGAAGT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate