DNAJB1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015938
Fusion event
HBV-DNAJB1 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1426
Orient
+
Host Sequence
Chromosome
chr19
Cytoband
p13.12
Reference genome
GRCh37/hg19
Start
14630475/14519663 (Hg38)
End
14630475/14519663 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
DNAJB1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-155-5p ; hsa-mir-122-5p ; hsa-mir-30a-5p ; hsa-mir-16-5p ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-10395/Upstream/446184; hsa-let-7e/Downstream/9880;
Nearest TSS
ENST00000633603/Upstream/1243; ENST00000599646/Downstream/9530;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/786, chr19-CpG: 90/Downstream/9404
Nearby gene
TECR
Nearest cancer related gene
DNAJB1(TSG, No orient, 0)
Upstream sequence
agaacagcccaggaaagacgcacctccaggattcaaccatcctccaccagctccctcccacaacacgtgggaattatgggagctacaagatgaggtttgg
Downstream sequence
ctgtctgcactgggtccccagtgcctggaacgcagtgagaacctcataaatattCCCCGTTCTTACACACGTGCTTCTTTTTCTTCCCCAACTACCTTTA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate