DOCK3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015939
Fusion event
HBV-DOCK3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1819
Orient
-
Host Sequence
Chromosome
chr3
Cytoband
P21.1
Reference genome
GRCh37/hg19
Start
50719003/50681572 (Hg38)
End
50719003/50681572 (Hg38)
Orient
+
Location type
Intron
Target gene
DOCK3
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-125a-5p ; hsa-mir-34a-5p ; hsa-mir-486-5p
Nearest miRNA
hsa-mir-12127/Upstream/6409; hsa-let-7g/Downstream/1586706;
Nearest TSS
ENST00000440867/Upstream/6331; ENST00000482262/Downstream/703475;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/5996, chr3-CpG: 91/Downstream/702983
Upstream sequence
CATAGTGCTGTGCAGGAAGCAACTTGCCTTGATGCCAGAATGAAATCCTAGAGTACATGTCTATGAATGAAGTATAAATTACAAAAGCACAGAATTGCCA
Downstream sequence
TAAAGGCTCTTAAAACCTTAAATTTTTTTTATACATCACCAAATTATTTTAGCTAAGTACTTGCAGTTGATTTGCTATATCACACCTTAGGGATACTCTA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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