VISDB Viral Integration Site DataBase

VIS ID

TVIS10015942

Fusion event

HBV-MSRB2 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Not given

Start

1720

Orient

+

Chromosome

chr10

Cytoband

p12.2

Reference genome

Start

End

23408286/23119357 (Hg38)

Orient

+

Location type

Exon

Target gene

miRNAs that regulate target gene

hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-561-5p ; hsa-mir-383-3p ; hsa-mir-3922-5p ; hsa-mir-6878-3p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-3934-5p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-150-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-498 ; hsa-mir-5571-5p ; hsa-mir-562 ; hsa-mir-5697 ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6778-3p ; hsa-mir-6814-5p

Nearest miRNA

hsa-mir-1265/Upstream/1622716; hsa-mir-107/Downstream/1156328;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/23208, chr10-CpG: 30/Downstream/53014

Upstream sequence

tgaatttatttgttaaaaatataaaattgccatacattttggttaattgacatcaaggaatgtggaaacttacccattgaatttaaacaataatctgagt

Downstream sequence

gtgactggttaatgaggctgaaaaagagtatcatgatttaatacactcatctactgattggtttcttccatacgtactgtggtactgaattatggacccc