Basic Information
VIS ID
TVIS10015944
Fusion event
HBV-SUGCT integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1660
Orient
-
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
40234459/40194860 (Hg38)
End
40234459/40194860 (Hg38)
Orient
-
Location type
Intron
Target gene
SUGCT
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1183/Upstream/3275428; hsa-mir-10399/Downstream/2956035;
Nearest TSS
ENST00000635602/Upstream/59844; ENST00000488110/Downstream/79651;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/59441, chr7-CpG: 26/Downstream/1510720
Upstream sequence
CCTCCTGGACACATAGCCCCTCTAGAGCtgtctttgacagtctcggctgccataacaaagtcccatagactggctgccttatcaacaatagatatctatt
Downstream sequence
TCAATTGTGTAAAGTTAAAATTCTATCATGTGGGGATTTGTTGAGTGGAAGTCTGACTCATGTTCACCTCTTCCATCAGCTTGCAGCTGTTTGTGATGTG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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