Basic Information
VIS ID
TVIS10015946
Fusion event
HBV-LOC110121230 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1836
Orient
+
Host Sequence
Chromosome
chr2
Cytoband
q37.3
Reference genome
GRCh37/hg19
Start
238224722/237316079 (Hg38)
End
238224722/237316079 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2J
Target gene
LOC110121230
Nearest miRNA
hsa-mir-10b/Upstream/4765506; hsa-mir-149/Downstream/194852;
Nearest TSS
ENST00000437798/Upstream/58988; ENST00000429898/Downstream/14101;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/229846, chr2-CpG: 22/Downstream/55753
Nearby gene
COL6A3
Upstream sequence
tagaaaaagagggaatctttcctaactcattttatgaggccagcatcatcctgataccaaagcctggcagagacacaacaaaaaaagagaattttagacc
Downstream sequence
CCTCTTTTGCCTCACAGAAAAACAAAGATAGAGACACTCTTGAGGTCCTTCTGCACAGCCCTAAACTTGTACTCAATCTTCGTACTGTTTTCCAAATCAC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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