Basic Information
VIS ID
TVIS10015948
Fusion event
HBV-chr19:q13.2 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1817
Orient
-
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
45444905/44941648 (Hg38)
End
45444905/44941648 (Hg38)
Orient
+
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/182927; hsa-let-7e/Downstream/495006;
Nearest TSS
ENST00000633603/Upstream/26779; ENST00000591600/Downstream/590;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/32305, chr19-CpG: 64/Downstream/13308
Nearby gene
APOC2
Upstream sequence
ctctaggctgcctccctaccctgggcctttgcacatgctgttccctctgcttttgtgagcagggtagacctgtgcaagtgacctcttctctctgaacctc
Downstream sequence
agtcttgctctgtcacccaggctggagtgcagtggtgtgatcgcggctcactgcagccttcacttcccgggttcaagccattctcctgcctcagcctccc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate