Basic Information
VIS ID
TVIS10015950
Fusion event
HBV-chr7:q11.23 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1814
Orient
+
Host Sequence
Chromosome
chr7
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
72974855/73560525 (Hg38)
End
72974855/73560525 (Hg38)
Orient
+
Fragile sites / regions
FRA7J
Nearest miRNA
hsa-mir-1183/Upstream/862547; hsa-mir-10399/Downstream/150792;
Nearest TSS
ENST00000635602/Upstream/2523; ENST00000324941/Downstream/10869;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/2742, chr7-CpG: 18/Downstream/10135
Nearby gene
BCL7B
Upstream sequence
tacagaactatagttgttgataagttatataaaggaaagtacaggggattgtaagagcatagactagggtgatgtctttggatctggtgtgagagatgtc
Downstream sequence
GCCCTTGAGACTTCTCCAGTTCTGCCCATAGATCCCCCTGGTTGAGGCACACAGCCCCTGTGTCTGTCTCACCCTTGTCCAAATCCTCCCACGTGAGGTT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate