Basic Information
VIS ID
TVIS10015955
Fusion event
HBV-chr12:p13.31 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1821
Orient
+
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
7953019/7800423 (Hg38)
End
7953019/7800423 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-141/Upstream/836232; hsa-let-7i/Downstream/1439044;
Nearest TSS
ENST00000382841/Upstream/10808; ENST00000428177/Downstream/32342;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/94234, chr12-CpG: 58/Downstream/72345
Nearby gene
NANOG
Nearest cancer related gene
NANOG(OG, No orient)
Upstream sequence
acagggtgaaagaagcttctgactgaactctgtaataattttgactaagcatgaattttcatgagcagaatcttggcggtggggtgcgaatgggaaatgc
Downstream sequence
agatatgagtgcagaagctgcagccaacagtgtgggtagacagggaggggcaaggcctgggagccctgcttgctttcttagtggggaggctcatagcctg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate