Basic Information
VIS ID
TVIS10015957
Fusion event
HBV-GS1-124K5.11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1755
Orient
+
Host Sequence
Chromosome
chr7
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
66054938/66589951 (Hg38)
End
66054938/66589951 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
GS1-124K5.11
Nearest miRNA
hsa-mir-1183/Upstream/1910775; hsa-mir-10399/Downstream/524371;
Nearest TSS
ENST00000635602/Upstream/96165; ENST00000449064/Downstream/38816;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/32660, chr7-CpG: 101/Downstream/1513
Nearby gene
KCTD7
Upstream sequence
CCAAGGGGATGGTGGTTGGGTGGAGGCCTGTAGGGGAAGCTGCCCGTTTCAATCCTCATCCACCTCCTCACCCTCTGACTCTTCGCCGCCGCCGCTGCCC
Downstream sequence
ctgagacaagaggatcgcttaagcctgggtggtggaggctgcagtgagctgtgttcccgccactgcattcgagagagagagagagacccAtttttttttt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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