Basic Information
VIS ID
TVIS10015960
Fusion event
HBV-LOC105375170 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1818
Orient
-
Host Sequence
Chromosome
chr7
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
17031634/16992010 (Hg38)
End
17031634/16992010 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105375170
Nearest miRNA
hsa-mir-339/Upstream/9924965; hsa-mir-10399/Downstream/1135210;
Nearest TSS
ENST00000635602/Upstream/75651; ENST00000475440/Downstream/140180;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/140547, chr7-CpG: 107/Downstream/306618
Upstream sequence
cataatgcagagttctaggaagatcaagtaaggtaagcatgcaaagtgcttaatactgtgcctggaacaccacacatgctcaacacgtgccagctttTAC
Downstream sequence
TCTTTCTTTCCTTtcttctctcctctcctctcctctcctttcctttctttccatttttgagacggagtttcactcttgttgcccaggatggagtgcagtg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate