Basic Information
VIS ID
TVIS10015964
Fusion event
HBV-chr18:q22.1 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1886
Orient
-
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
64028253/66361016 (Hg38)
End
64028253/66361016 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1-2/Upstream/7909858; hsa-mir-5011/Downstream/720568;
Nearest TSS
ENST00000575820/Upstream/440074; ENST00000581951/Downstream/211155;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/609612, chr18-CpG: 83/Downstream/1154984
Upstream sequence
GGAGCGAATCACCCACAATGATTGGAGCCTGCTTCCAGCTGCAGCTAGTGGAAAGTTACCTGATTTTCACTGTTGGTGAAGCCCAGTCTTGCAGCCTGTA
Downstream sequence
TAAGATGAATGTCTGTATTTCTTGTTTTTCCTTTTTTTAAAATTTCAGAATGAAGTTACAGgacttccacttccaggaaaatggagtagatgtacttttc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate