Basic Information
VIS ID
TVIS10015967
Fusion event
HBV-PHF24 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1825
Orient
+
Host Sequence
Chromosome
chr9
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
34876708/34876711 (Hg38)
End
34876708/34876711 (Hg38)
Orient
+
Location type
Intronic
Target gene
PHF24
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-101-2/Upstream/1408776; hsa-let-7a-1/Downstream/731383;
Nearest TSS
ENST00000422679/Upstream/147244; ENST00000486477/Downstream/19011;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/66479, chr9-CpG: 93/Downstream/81009
Nearby gene
FAM205BP
Upstream sequence
CCTAGGTGTCCGTTTCTGGGTGAAGTCctggaagcagataaatgtttgcagaggtgatctatgtgtggtgggattaaagagatgaatatattttactgtt
Downstream sequence
TGATTACTTCATTATCATTTAAAAACGGATTTCCCTGTGTATTAGATGTTGTGGATTGCATTCCTAACTAAAAGCTTACATACATTTCTGTTTGAGCTTC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate