Basic Information
VIS ID
TVIS10015976
Fusion event
HBV-IGH integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1825
Orient
-
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37/hg19
Start
107050990/106594995 (Hg38)
End
107050990/106594995 (Hg38)
Orient
-
Location type
Intronic
Target gene
IGH
Nearest miRNA
hsa-mir-1185-1/Upstream/735442; hsa-mir-5195/Downstream/255890;
Nearest TSS
ENST00000550708/Upstream/1648; ENST00000519538/Downstream/4929;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/112184, chr14-CpG: 17/Downstream/217863
Nearby gene
LINC00221
Upstream sequence
aaagtgctgggattacaggcgtgagccaccgcacccagcATCACCATGCTTTTCTGCATCCAAAATAGGTCACCTGCAGCAACGTGGGAAGCCTTGTACA
Downstream sequence
aggcatgggctatataaacatctggacgaatattttaattctgagcaattatccggcaaatcatgccaggtgactggaataaatagggtccccctaaccc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate