Basic Information
VIS ID
TVIS10015977
Fusion event
HBV-ZRANB2-AS1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1834
Orient
-
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
71520087/71054404 (Hg38)
End
71520087/71054404 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
ZRANB2-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/2870794; hsa-mir-11399/Downstream/13227;
Nearest TSS
ENST00000473358/Upstream/5549; ENST00000426999/Downstream/3919;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/6283, chr1-CpG: 20/Downstream/26399
Nearby gene
PTGER3
Upstream sequence
CTCCGCCCCTCCATGAAGAGCCACAGGCACCGTGGAAAGGGCTCTGGGCCAGGGTTGGAGGAACCGTCATGGTCGACCACGCTGACCATGCCCACGCTCT
Downstream sequence
GGGCCCCTTGCCTGTGGGTGAGCAGTTGGGGGTTGCTGTGGCCCGGGGTCGCTCGTGTGGCCCCAGTTGTCTAAGATGACCTGGCTCGCCCATCTGGAGG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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