Basic Information
VIS ID
TVIS10015981
Fusion event
HBV-chr4:q33 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1821
Orient
+
Host Sequence
Chromosome
chr4
Cytoband
q33
Reference genome
GRCh37/hg19
Start
171763477/170842326 (Hg38)
End
171763477/170842326 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-12113/Upstream/5455989; hsa-mir-1305/Downstream/343858;
Nearest TSS
ENST00000502981/Upstream/98608; ENST00000505329/Downstream/198276;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/751974, chr4-CpG: 117/Downstream/970257
Upstream sequence
AAACGACTTACATAAGAAGATCACATCTGAATTGAGATACATTATTATTTACATTCATAATGGAAATAACAAAATTAATCACATTAGGTCTTATAAATAA
Downstream sequence
tatgacatggatgaatctcacagaataatattgagtggaaggaactagacacaaaagaacatgtactgtaagatttcatttgcctaaaggtttaaaacaa
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate